PEEK PROJECTClinical decision poster
Rural private-practice physiotherapy · Student project resource

Recognising rare serious pathology behind common presentations

A clinical decision-making poster for noticing when a familiar presentation does not follow the expected pattern—and selecting the safest next action.

Central question
What does not fit, how concerning is the pattern, and what should happen next?

Use
Scan the overview, then expand the relevant presentation below.

Educational resource: supports recognition, referral and safety-netting. It does not diagnose or replace local emergency and referral procedures.

01

Decision-making overview

Does the whole pattern fit?

1

Start with the familiar presentation

Complete the usual subjective and objective assessment.

2

Look for the mismatch

Consider trajectory, function, distribution, systemic features and risk context. One red flag is rarely enough.

3

Choose the safest pathway

Expected patternManage, review and safety-netConcerning clusterPrompt medical assessmentEmergency featuresImmediate escalation
4

Communicate and close the loop

Describe observable findings, uncertainty and urgency. Document the plan and give specific safety-net advice.

02

Expandable clinical pathways

Five common presentations, five important mismatches

Open the presentation that best matches the patient in front of you.
01Common presentationLow back painBroader considerationMultiple myelomaExplore +
Key clinical signalPersistent, progressive pain with systemic or haematological clues

A. Expected pattern

  • A plausible mechanical onset or loading relationship
  • Symptoms improve or fluctuate with appropriate care
  • No progressive systemic change

B. Notice the mismatch

  • Progressive pain without a clear injury
  • Increasing fatigue or reduced exercise tolerance
  • Recurrent infections, unexplained weight change or fracture history
  • Pain increasingly affecting rest or sleep

C. Focused assessment

  • Clarify trajectory and functional change
  • Screen neurological status and immediate spinal emergencies
  • Ask about constitutional, infection, renal, calcium and fracture clues

Prompt medical assessment

An unexplained, progressive pattern with systemic features warrants prompt medical assessment even when acute neurological findings are absent.

Immediate escalation

Escalate immediately for acute neurological compromise, severe systemic deterioration, confusion, markedly reduced urine output or another medical emergency.

Referral communication

Describe the pain trajectory, associated systemic findings, examination, why the pattern is unexpected and the requested urgency—without claiming a diagnosis.

Safety-net

Advise urgent review for new weakness, bladder or bowel change, saddle symptoms, confusion, severe deterioration or rapidly escalating pain.

Key supporting sources: (Leukaemia Foundation & Australian Government Department of Health, 2021; NICE, 2016, 2025; Seesaghur et al., 2021; Shephard et al., 2015). Full source list below.

Clinical example

A 68-year-old farmer has eight weeks of worsening low back pain without a clear injury. Work and sleep are now limited. He also reports increasing fatigue, reduced exercise tolerance and two recent chest infections. The pattern should trigger broader consideration and prompt medical assessment.

Reasoning focus: Identify the mismatch, exclude immediate danger, communicate the pattern and select referral urgency without diagnosing.

Evidence traceability: the workbook maps each published statement and clinical example to its supporting evidence items and verified source register.

02Common presentationNeck painBroader considerationDegenerative cervical myelopathyExplore +
Key clinical signalProgressive hand dysfunction with gait or multi-limb change

A. Expected pattern

  • Local or referred neck symptoms
  • A coherent mechanical or peripheral pattern
  • Stable dexterity, gait and lower-limb function

B. Notice the mismatch

  • Dropping objects or difficulty with buttons
  • Gait imbalance or reduced confidence on uneven ground
  • Leg heaviness or multi-limb sensory change
  • Progressive function across more than one neurological domain

C. Focused assessment

  • Ask about dexterity, gait, falls and multi-limb symptoms
  • Complete an appropriate neurological examination
  • Screen bladder or bowel change and rate of deterioration

Prompt medical assessment

Progressive hand dysfunction plus gait or upper-motor-neuron findings warrants prompt medical assessment. No single test rules DCM in or out.

Immediate escalation

Escalate immediately for rapid neurological deterioration, major new weakness, acute bladder or bowel dysfunction or another emergency presentation.

Referral communication

Report functional trajectory, multi-limb symptoms, neurological findings and the need for assessment of possible cervical cord dysfunction.

Safety-net

Advise urgent review for new falls, rapidly worsening balance, weakness, loss of hand function or bladder/bowel change.

Key supporting sources: (Davies et al., 2018; Fehlings et al., 2017; Jiang et al., 2024; Milligan et al., 2019). Full source list below.

Clinical example

A 64-year-old farm manager has four months of neck stiffness and bilateral hand tingling. He is dropping fencing clips, struggles with buttons and feels less steady on uneven paddocks. This is not an isolated neck presentation and warrants prompt medical assessment.

Reasoning focus: Identify the mismatch, exclude immediate danger, communicate the pattern and select referral urgency without diagnosing.

Evidence traceability: the workbook maps each published statement and clinical example to its supporting evidence items and verified source register.

03Common presentationShoulder painBroader considerationPolymyalgia rheumaticaExplore +
Key clinical signalBilateral stiffness with hip-girdle, functional or systemic change

A. Expected pattern

  • A local shoulder pattern
  • Symptoms linked to shoulder movement or loading
  • No evolving bilateral or systemic picture

B. Notice the mismatch

  • New bilateral shoulder symptoms
  • Prolonged morning or post-rest stiffness
  • Difficulty dressing or rising from a chair
  • Fatigue, reduced appetite or hip-girdle symptoms

C. Focused assessment

  • Clarify distribution, stiffness duration and function
  • Distinguish pain-limited effort from objective weakness
  • Always screen for new headache, scalp tenderness, jaw pain and visual symptoms

Prompt medical assessment

A new bilateral, stiffness-led pattern in an older adult warrants prompt medical assessment for inflammatory and other non-musculoskeletal causes.

Immediate escalation

New visual disturbance or cranial ischaemic symptoms require immediate same-day medical escalation because of possible giant cell arteritis.

Referral communication

Communicate bilateral distribution, stiffness, functional and systemic change, examination findings and the giant cell arteritis screen.

Safety-net

Explain that new headache, scalp tenderness, jaw pain or any visual symptom requires urgent same-day review.

Key supporting sources: (Dasgupta et al., 2012; Dejaco et al., 2015; Lundberg et al., 2022; NICE, n.d.). Full source list below.

Clinical example

A 72-year-old cattle farmer develops bilateral shoulder pain, about an hour of morning stiffness, difficulty dressing and rising from a chair, fatigue and reduced appetite. The broader pattern warrants prompt assessment; a GCA screen determines whether escalation becomes immediate.

Reasoning focus: Identify the mismatch, exclude immediate danger, communicate the pattern and select referral urgency without diagnosing.

Evidence traceability: the workbook maps each published statement and clinical example to its supporting evidence items and verified source register.

04Common presentationHip painBroader considerationAvascular necrosisExplore +
Key clinical signalProgressive deep hip pain with a meaningful risk context

A. Expected pattern

  • A plausible local mechanical explanation
  • Symptoms respond predictably to load modification
  • No major osseous risk context

B. Notice the mismatch

  • Progressive deep groin or anterior-thigh pain
  • Increasing weight-bearing limitation or night pain
  • Meaningful corticosteroid exposure
  • Previous hip trauma or relevant medical history

C. Focused assessment

  • Clarify location, trajectory and weight-bearing behaviour
  • Ask about corticosteroids, alcohol, trauma and relevant conditions
  • Assess gait and hip movement without repeatedly provoking severe pain

Prompt medical assessment

Progressive deep hip pain with a relevant exposure or risk context warrants prompt medical assessment. Early plain radiographs may be normal.

Immediate escalation

Escalate immediately after acute trauma, inability to weight bear, severe systemic illness, neurovascular compromise or another emergency feature.

Referral communication

Describe the deep pain trajectory, loading limitation, risk context, examination and concern for osseous or intra-articular pathology.

Safety-net

Reduce provocative loading and advise urgent review for sudden deterioration, inability to weight bear, fever or neurovascular symptoms.

Key supporting sources: (American College of Radiology, 2022; George & Lane, 2022; Petek et al., 2019; Zhao et al., 2020). Full source list below.

Clinical example

A 43-year-old livestock agent has six weeks of progressive deep groin pain, an antalgic gait and reduced internal rotation. Several courses of high-dose corticosteroids make this more than a routine hip-flexor presentation and support prompt medical assessment.

Reasoning focus: Identify the mismatch, exclude immediate danger, communicate the pattern and select referral urgency without diagnosing.

Evidence traceability: the workbook maps each published statement and clinical example to its supporting evidence items and verified source register.

05Common presentationCalf painBroader considerationPopliteal artery entrapment syndromeExplore +
Key clinical signalReproducible exertional symptoms with distal vascular change

A. Expected pattern

  • A musculoskeletal onset or training-load relationship
  • Local symptoms behave consistently with tissue recovery
  • No distal temperature, colour or neurological change

B. Notice the mismatch

  • Symptoms begin at a reproducible exercise threshold
  • Rapid relief after stopping
  • Episodic foot coldness, colour change or tingling
  • Young active person without typical atherosclerotic risk

C. Focused assessment

  • Clarify exercise threshold and relief with rest
  • Check vascular and neurological status at rest
  • Use provocation cautiously; a pulse manoeuvre alone is not diagnostic

Prompt medical assessment

A reproducible exercise–rest pattern with distal change warrants prompt medical or vascular assessment. Normal resting findings do not exclude dynamic compression.

Immediate escalation

Persistent severe pain, pallor, coldness, numbness, weakness or pulse loss requires emergency escalation for possible acute limb ischaemia.

Referral communication

Report the exercise–rest pattern, distal symptoms, resting and provoked findings and request dynamic medical vascular assessment.

Safety-net

Modify provoking exercise and explain the acute limb-ischaemia symptoms that require immediate emergency review.

Key supporting sources: (Bradshaw et al., 2021; Hislop et al., 2014; Sinha et al., 2012; Barrett et al., 2024). Full source list below.

Clinical example

A 24-year-old agricultural worker and runner develops calf tightness after a reproducible running interval. It settles with rest, but the foot can become cold and tingly. Normal resting pulses do not close the differential; prompt vascular assessment is appropriate.

Reasoning focus: Identify the mismatch, exclude immediate danger, communicate the pattern and select referral urgency without diagnosing.

Evidence traceability: the workbook maps each published statement and clinical example to its supporting evidence items and verified source register.

03

Project method

From evidence to a scan-first resource

The method is shown so the clinical content can be traced and reviewed.
01

Define the gap

Focus on high-impact, low-prevalence conditions that may initially resemble common rural private-practice presentations.

02

Search and appraise

Build a 15-item evidence matrix and nine-source register for each pathology, recording relevance, limitations and confidence.

03

Translate evidence

Organise each pathway around the expected pattern, the mismatch, focused assessment, urgency, referral and safety-netting.

04

Apply safeguards

Avoid diagnostic shortcuts, preserve physiotherapy scope and distinguish prompt medical assessment from immediate escalation.

04

Evidence and governance

Support for clinical judgement—not a replacement

Evidence-informed
Pathways are based on verified clinical literature and authoritative guidance retained in the project evidence workbook.

Scope-aware
The resource prompts recognition, urgency, referral and safety-netting. It does not diagnose or prescribe medical investigation.

Rural context
Guidance supports decision-making where access and referral pathways may vary; clinicians should follow local emergency and escalation procedures.

Evidence reviewed: August 2026

Open each pathway to view the complete set of sources used to develop its published clinical content.

Low back painMultiple myeloma 9 sources
  1. Bowcock, S., Atkin, C., Iqbal, G., Pratt, G., Yong, K., Neal, R. D., Planche, T., Karunanithi, K., Jenkins, S., Stern, S., Arnott, S., Toth, P., Wandroo, F., Dunn, J., & Drayson, M. T. (2023). Presenting symptoms in newly diagnosed myeloma, relation to organ damage, and implications for symptom-directed screening: A secondary analysis from the TEAMM trial. Cancers, 15(13), 3337. https://doi.org/10.3390/cancers15133337
  2. Goldschmidt, N., Zamir, L., Poperno, A., Kahan, N. R., & Paltiel, O. (2016). Presenting signs of multiple myeloma and the effect of diagnostic delay on the prognosis. The Journal of the American Board of Family Medicine, 29(6), 702–709. https://doi.org/10.3122/jabfm.2016.06.150393
  3. Koshiaris, C., Van den Bruel, A., Oke, J. L., Nicholson, B. D., Shephard, E., Braddick, M., & Hamilton, W. (2018). Early detection of multiple myeloma in primary care using blood tests: A case–control study in primary care. British Journal of General Practice, 68(674), e586–e593. https://doi.org/10.3399/bjgp18x698357
  4. Leukaemia Foundation & Australian Government Department of Health. (2021). Optimal care pathway for people with multiple myeloma (1st ed.). https://www.cancer.org.au/assets/pdf/ocp/multiple-myeloma-1st-edition
  5. National Institute for Health and Care Excellence. (2016). Myeloma: Diagnosis and management (NICE Guideline NG35). https://www.nice.org.uk/guidance/ng35
  6. National Institute for Health and Care Excellence. (2025). Suspected cancer: Recognition and referral (NICE Guideline NG12). https://www.nice.org.uk/guidance/ng12
  7. Rajkumar, S. V., Dimopoulos, M. A., Palumbo, A., Blade, J., Merlini, G., Mateos, M.-V., Kumar, S., Hillengass, J., Kastritis, E., Richardson, P., Landgren, O., Paiva, B., Dispenzieri, A., Weiss, B., LeLeu, X., Zweegman, S., Lonial, S., Rosinol, L., Zamagni, E., ... Miguel, J. F. S. (2014). International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. The Lancet Oncology, 15(12), e538–e548. https://doi.org/10.1016/S1470-2045(14)70442-5
  8. Seesaghur, A., Petruski-Ivleva, N., Banks, V. L., Wang, J. R., Abbasi, A., Neasham, D., & Ramasamy, K. (2021). Clinical features and diagnosis of multiple myeloma: A population-based cohort study in primary care. BMJ Open, 11(10), e052759. https://doi.org/10.1136/bmjopen-2021-052759
  9. Shephard, E. A., Neal, R. D., Rose, P., Walter, F. M., Litt, E. J., & Hamilton, W. (2015). Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: A large case-control study using electronic records. British Journal of General Practice, 65(631), e106–e113. https://doi.org/10.3399/bjgp15X683545
Neck painDegenerative cervical myelopathy 9 sources
  1. Cervellini, M., Feller, D., Maselli, F., Rossettini, G., Cook, C., Tabrah, J., Chauhan, R. V., Taylor, A., Kerry, R., Young, I., Dunning, J., Hutting, N., & Mourad, F. (2025). Understanding degenerative cervical myelopathy in musculoskeletal practice. Journal of Manual & Manipulative Therapy, 33(3), 207–223. https://doi.org/10.1080/10669817.2025.2465728
  2. Davies, B. M., Mowforth, O. D., Smith, E. K., & Kotter, M. R. N. (2018). Degenerative cervical myelopathy. BMJ, 360, k186. https://doi.org/10.1136/bmj.k186
  3. Fehlings, M. G., et al. (2017). A clinical practice guideline for the management of patients with degenerative cervical myelopathy. Global Spine Journal, 7(3 Suppl.), 70S–83S. https://doi.org/10.1177/2192568217701914
  4. Hilton, B., Gardner, E. L., Jiang, Z., Tetreault, L., Wilson, J. R. F., Zipser, C. M., Riew, K. D., Guest, J. D., Harrop, J. S., Fehlings, M. G., Rodrigues-Pinto, R., Rahimi-Movaghar, V., Aarabi, B., Koljonen, P. A., Kotter, M. R. N., Davies, B. M., & Kwon, B. K. (2022). Establishing diagnostic criteria for degenerative cervical myelopathy. Global Spine Journal, 12(1_suppl), 55S–63S. https://doi.org/10.1177/21925682211030871
  5. Hilton, B., Tempest-Mitchell, J., Davies, B. M., & Kotter, M. R. N. (2019). Route to diagnosis of degenerative cervical myelopathy in a UK healthcare system: A retrospective cohort study. BMJ Open, 9(5), e027000. https://doi.org/10.1136/bmjopen-2018-027000
  6. Hilton, B., Tempest-Mitchell, J., Davies, B., & Kotter, M. (2018). Assessment of degenerative cervical myelopathy differs between specialists and may influence time to diagnosis and clinical outcomes. PLOS ONE, 13(12), e0207709. https://doi.org/10.1371/journal.pone.0207709
  7. Jiang, Z., et al. (2024). The value of clinical signs in the diagnosis of degenerative cervical myelopathy: A systematic review and meta-analysis. Global Spine Journal, 14(4), 1369–1394. https://doi.org/10.1177/21925682231209869
  8. Malone, A., Sofiany, M., Dawood, G., Wright, J., Ryan, R., Treanor, C., Gallagher, C., Lenehan, W., Doyle, F., & Bolger, C. (2025). Duration of symptoms before diagnosis in degenerative cervical myelopathy: A systematic review and meta-analysis. Brain and Spine, 5, 104252. https://doi.org/10.1016/j.bas.2025.104252
  9. Milligan, J., Ryan, K., Fehlings, M., & Bauman, C. (2019). Degenerative cervical myelopathy: Diagnosis and management in primary care. Canadian Family Physician, 65(9), 619–624. https://pmc.ncbi.nlm.nih.gov/articles/PMC6741789/
Shoulder painPolymyalgia rheumatica 9 sources
  1. American College of Rheumatology. (n.d.). Polymyalgia rheumatica. https://rheumatology.org/patients/polymyalgia-rheumatica
  2. Dasgupta, B., Borg, F. A., Hassan, N., Barraclough, K., Bourke, B., Fulcher, J., Hollywood, J., Hutchings, A., Kyle, V., Nott, J., Power, M., & Samanta, A. (2010). BSR and BHPR guidelines for the management of polymyalgia rheumatica. Rheumatology, 49(1), 186–190. https://doi.org/10.1093/rheumatology/kep303a
  3. Dasgupta, B., et al. (2012). 2012 provisional classification criteria for polymyalgia rheumatica. Annals of the Rheumatic Diseases, 71(4), 484-492. https://doi.org/10.1136/annrheumdis-2011-200329
  4. Dejaco, C., et al. (2015). 2015 recommendations for the management of polymyalgia rheumatica. Arthritis & Rheumatology, 67(10), 2569–2580. https://doi.org/10.1002/art.39333
  5. Florescu, M. M., Bobircă, F., Florescu, A., Pădureanu, V., Bobircă, A., Ciurea, P. L., Criveanu, C., Florescu, L. M., & Mușetescu, A. E. (2023). Polymyalgia rheumatica: An update. Experimental and Therapeutic Medicine, 26(6), 543. https://doi.org/10.3892/etm.2023.12242
  6. Lundberg, I. E., et al. (2022). An update on polymyalgia rheumatica. Journal of Internal Medicine, 292(5), 717-732. https://pmc.ncbi.nlm.nih.gov/articles/PMC9796644/
  7. Michet, C. J., & Matteson, E. L. (2008). Polymyalgia rheumatica. BMJ, 336(7647), 765–769. https://doi.org/10.1136/bmj.39514.653588.80
  8. National Institute for Health and Care Excellence. (n.d.). Giant cell arteritis: Diagnosis. Retrieved July 27, 2026, from https://cks.nice.org.uk/topics/giant-cell-arteritis/diagnosis/diagnosis/
  9. National Institute for Health and Care Excellence. (n.d.). Giant cell arteritis: Management. Retrieved July 27, 2026, from https://cks.nice.org.uk/topics/giant-cell-arteritis/management/management/
Hip painAvascular necrosis 9 sources
  1. American Academy of Orthopaedic Surgeons. (n.d.). Osteonecrosis of the hip. OrthoInfo. https://orthoinfo.aaos.org/en/diseases--conditions/osteonecrosis-of-the-hip/
  2. American College of Radiology. (2022). ACR Appropriateness Criteria: Osteonecrosis. https://acsearch.acr.org/docs/69420/Narrative/
  3. Choi, H. R., Steinberg, M. E., & Cheng, E. Y. (2015). Osteonecrosis of the femoral head: Diagnosis and classification systems. Current Reviews in Musculoskeletal Medicine, 8(3), 210–220. https://doi.org/10.1007/s12178-015-9278-7
  4. George, G., & Lane, J. M. (2022). Osteonecrosis of the femoral head. JAAOS: Global Research and Reviews, 6(5), e21.00176. https://doi.org/10.5435/JAAOSGlobal-D-21-00176
  5. Hines, J. T., et al. (2021). Osteonecrosis of the femoral head: An updated review of ARCO on pathogenesis, staging and treatment. Journal of Korean Medical Science, 36(24), e177. https://doi.org/10.3346/jkms.2021.36.e177
  6. Petek, D., Hannouche, D., & Suva, D. (2019). Osteonecrosis of the femoral head. EFORT Open Reviews, 4(3), 85-97. https://pmc.ncbi.nlm.nih.gov/articles/PMC6440301/
  7. Shah, K. N., Racine, J., Jones, L. C., & Aaron, R. K. (2015). Pathophysiology and risk factors for osteonecrosis. Current Reviews in Musculoskeletal Medicine, 8(3), 201–209. https://doi.org/10.1007/s12178-015-9277-8
  8. Yoon, B.-H., Mont, M. A., Koo, K.-H., Chen, C.-H., Cheng, E. Y., Cui, Q., Drescher, W., Gangji, V., Goodman, S. B., Ha, Y.-C., Hernigou, P., Hungerford, M. W., Iorio, R., Jo, W.-L., Jones, L. C., Khanduja, V., Kim, H. K. W., Kim, S.-Y., Kim, T.-Y., ... Zhao, D. W. (2020). The 2019 revised version of Association Research Circulation Osseous staging system of osteonecrosis of the femoral head. The Journal of Arthroplasty, 35(4), 933–940. https://doi.org/10.1016/j.arth.2019.11.029
  9. Zhao, D., et al. (2020). Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults. Journal of Orthopaedic Translation, 21, 100–110. https://doi.org/10.1016/j.jot.2019.12.004
Calf painPopliteal artery entrapment syndrome 9 sources
  1. Barrett, D. W., et al. (2024). Improving duplex ultrasound methods for diagnosing functional popliteal artery entrapment syndrome. Scandinavian Journal of Medicine & Science in Sports, 34(3), e14592. https://doi.org/10.1111/sms.14592
  2. Bradshaw, S., et al. (2021). Popliteal artery entrapment syndrome. Cardiovascular Diagnosis and Therapy, 11(5), 1159-1167. https://pmc.ncbi.nlm.nih.gov/articles/PMC8569273/
  3. Davis, D. D., & Kane, S. M. (2023). Popliteal artery entrapment syndrome. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK441965/
  4. Gaunder, C., McKinney, B., & Rivera, J. (2017). Popliteal artery entrapment or chronic exertional compartment syndrome? Case Reports in Medicine, 2017, 1–5. https://doi.org/10.1155/2017/6981047
  5. Gokkus, K., Sagtas, E., Bakalim, T., Taskaya, E., & Aydin, A. T. (2014). Popliteal entrapment syndrome: A systematic review of the literature and case presentation. Muscles, Ligaments and Tendons Journal, 4(2), 141–148. https://pmc.ncbi.nlm.nih.gov/articles/PMC4187583/
  6. Hislop, M., Kennedy, D., Cramp, B., & Dhupelia, S. (2014). Functional popliteal artery entrapment syndrome: Poorly understood and frequently missed? Journal of Sports Medicine, 2014, 105953. https://pmc.ncbi.nlm.nih.gov/articles/PMC4590902/
  7. Mayo Clinic. (2025). Popliteal artery entrapment syndrome: Symptoms and causes. https://www.mayoclinic.org/diseases-conditions/popliteal-artery-entrapment/symptoms-causes/syc-20465211
  8. Sinha, S., et al. (2012). Popliteal entrapment syndrome. Journal of Vascular Surgery, 55(1), 252-262.e30. https://pubmed.ncbi.nlm.nih.gov/22116047/
  9. Williams, C., Kennedy, D., Bastian-Jordan, M., Hislop, M., Cramp, B., & Dhupelia, S. (2015). A new diagnostic approach to popliteal artery entrapment syndrome. Journal of Medical Radiation Sciences, 62(3), 226–229. https://doi.org/10.1002/jmrs.121

All 45 verified sources from the project evidence register are included above. The evidence workbook provides claim-level traceability, limitations and confidence ratings. Evidence was current at the time of website development and should be used alongside current clinical guidance and local referral pathways.